CYP3A7 and SGCE

Data Source:
BioGRID (proximity labelling technology)

		CYP3A7	SGCE
Description		cytochrome P450 family 3 subfamily A member 7	sarcoglycan epsilon
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Golgi Apparatus Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Dendrite Membrane Sarcolemma
	Molecular Function	Monooxygenase Activity Iron Ion Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxygen Binding Heme Binding Testosterone 6-beta-hydroxylase Activity Aromatase Activity Estrogen 16-alpha-hydroxylase Activity Estrogen 2-hydroxylase Activity
	Biological Process	Lipid Hydroxylation Steroid Biosynthetic Process Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Oxidative Demethylation	Cell-matrix Adhesion Muscle Organ Development
Pathways		Xenobiotics
Drugs		Cannabidiol Diacerein Nabiximols
Diseases			Primary torsion dystonia (PTD)
GWAS		Blood protein levels ( 29875488) Endometrial cancer ( 30093612) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes			3 interacting genes: ARIH2 CWC15 PPP1CC
Entrez ID		1551	8910
HPRD ID		05630	04999
Ensembl ID		ENSG00000160870	ENSG00000127990
Uniprot IDs		P24462	A0A0S2Z4P5 A0A2R8Y5J3 A0A2R8YGQ3 A0A2R8YH84 B4DP78 C9JR67 E9PEH6 O43556
PDB IDs
Enriched GO Terms of Interacting Partners?
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