JAKMIP1 and HTRA3

		JAKMIP1	HTRA3
Description		janus kinase and microtubule interacting protein 1	HtrA serine peptidase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Cytoskeleton Extrinsic Component Of Membrane Ribonucleoprotein Complex	Extracellular Region
	Molecular Function	RNA Binding Protein Binding Microtubule Binding Kinase Binding GABA Receptor Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Insulin-like Growth Factor Binding Serine-type Peptidase Activity Identical Protein Binding
	Biological Process	Protein Transport Cognition	Proteolysis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241) Response to angiotensin II receptor blocker therapy ( 22566498) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)	Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Interacting Genes		19 interacting genes: BLK C18orf25 CBX8 CHRM3 DDX6 ENKD1 GABBR1 IL16 JAK1 MCRS1 MRPL11 PSMB1 SCNM1 TSGA10IP TYK2 USP2 YES1 YWHAG ZNHIT2
Entrez ID		152789	94031
HPRD ID		11292	08821
Ensembl ID		ENSG00000152969	ENSG00000170801
Uniprot IDs		B3KWB6 Q96N16	P83110
PDB IDs			2P3W 4RI0
Enriched GO Terms of Interacting Partners?
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