CNTN4 and PRICKLE4

Data Source:
BioGRID (two hybrid)

		CNTN4	PRICKLE4
Description		contactin 4	prickle planar cell polarity protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Axon Anchored Component Of Membrane	Stress Fiber Nucleus Adherens Junction Z Disc Filamentous Actin
	Molecular Function	Cell-cell Adhesion Mediator Activity	Molecular_function Actin Binding Zinc Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Neuron Cell-cell Adhesion Nervous System Development Axonogenesis Axon Guidance Axonal Fasciculation Brain Development Neuron Projection Development Negative Regulation Of Neuron Differentiation Regulation Of Synaptic Plasticity Dendrite Self-avoidance	Heart Development Biological_process Actin Cytoskeleton Organization Muscle Structure Development
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Acenocoumarol maintenance dosage ( 19578179) Amyotrophic lateral sclerosis ( 19451621) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Atypical femoral fracture in phosphonate treatment ( 31006051) Autism spectrum disorder or schizophrenia ( 28540026) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood pressure ( 17903302) Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576 29875488) Body mass index (change over time) in chronic obstructive pulmonary disease ( 28044437) Brain connectivity ( 23471985) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime sleep phenotypes ( 27126917) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration ( 29346644) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 31647587) High myopia ( 32428537) Intake of total sugars ( 31005972) Intelligence ( 22449649) Metabolite levels ( 23823483) Middle childhood and early adolescence aggressive behavior ( 26087016) Night sleep phenotypes ( 27126917) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to aripiprazole in schizophrenia ( 29503163) Restless legs syndrome ( 29029846) Schizophrenia ( 28991256 25056061 29483656 30285260 26198764) Sensorimotor dexterity ( 31596458) Serum immune biomarker levels ( 32066700) Serum uric acid levels ( 24379826) Thiopurine-induced pancreatitis in inflammatory bowel disease ( 29923122) Total ventricular volume ( 21116278) White blood cell count (basophil) ( 27863252)
Interacting Genes		2 interacting genes: BARD1 BRCA1	9 interacting genes: AGXT GNE HOXA1 MTDH NEK6 OTX1 PLEKHN1 ZNF417 ZNF587
Entrez ID		152330	29964
HPRD ID		16239	12884
Ensembl ID		ENSG00000144619	ENSG00000278224
Uniprot IDs		Q8IWV2	Q2TBC4
PDB IDs
Enriched GO Terms of Interacting Partners?
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