NFAM1 and CHADL

Data Source:
HPRD (in vivo)

		NFAM1	CHADL
Description		NFAT activating protein with ITAM motif 1	chondroadherin like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Membrane Raft	Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Collagen Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance Collagen Fibril Binding
	Biological Process	Positive Regulation Of Cytokine Production Inflammatory Response Signal Transduction B Cell Differentiation Intracellular Signal Transduction Neutrophil Degranulation Regulation Of B Cell Differentiation B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity	Negative Regulation Of Chondrocyte Differentiation Negative Regulation Of Collagen Fibril Organization
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Machado-Joseph disease (age at onset) ( 32205469) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) Feeling worry ( 29500382) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Neuroticism ( 29255261 27918536) Osteoarthritis (hip) ( 30374069) Osteoarthritis (with total hip replacement) ( 28319091) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: BCL11A MAL2 SYK TCF4 ZAP70
Entrez ID		150372	150356
HPRD ID		16380	19495
Ensembl ID		ENSG00000235568	ENSG00000100399
Uniprot IDs		Q8NET5	Q6NUI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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