SAMD13 and NEGR1

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SAMD13	NEGR1
Description		sterile alpha motif domain containing 13	neuronal growth regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Chromatin Binding Histone Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Locomotory Behavior Feeding Behavior Positive Regulation Of Neuron Projection Development Cell-cell Adhesion
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Metabolite levels ( 23823483) Obesity-related traits ( 23251661)	Adult body size ( 32376654) Alcohol consumption (drinks per week) ( 30643258) Allergic rhinitis ( 30013184) Alzheimer's disease (late onset) ( 30820047) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 29273806) Asthma and major depressive disorder ( 31619474) Beef consumption ( 32066663) Bipolar disorder or body mass index ( 31754094) Blood protein levels ( 30072576) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 31888951 23563607 26426971 19079260 19079261 26961502 23669352 28892062 25673413 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Broad depression or major depressive disorder (self-reported) ( 30626913) Childhood body mass index ( 33045005 26604143) Chromium levels ( 26025379) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression ( 29700475) Diffusing capacity of carbon monoxide ( 30694715) Experiencing mood swings ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 17903294) Hip circumference ( 25673412) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Meat-related diet ( 32066663) Menarche (age at onset) ( 25231870) Mental health study participation (completed survey) ( 31263887) Mood instability ( 31168069) Neurociticism ( 29500382) Number of sexual partners ( 30643258) Obesity ( 23563607) Obesity (early onset extreme) ( 23563609) Obesity (extreme) ( 30677029 31888951) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Rosacea symptom severity ( 29771307) Self-reported risk-taking behaviour ( 30271922) Smoking status (ever vs never smokers) ( 30643258) Subcutaneous adipose tissue ( 22589738) Systemic lupus erythematosus ( 18204098) Urinary sodium excretion ( 31409800) Venlafaxine response in generalised anxiety disorder (HAMA-A score reduction after 24 weeks) ( 28437668) Vigorous physical activity ( 29899525) Waist circumference ( 25673412) Weight ( 19079260)
Interacting Genes			2 interacting genes: LSAMP NTM
Entrez ID		148418	257194
HPRD ID		17302	14820
Ensembl ID		ENSG00000203943	ENSG00000172260
Uniprot IDs		Q5VXD3	Q7Z3B1
PDB IDs			6DLD 6U6T
Enriched GO Terms of Interacting Partners?
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