VTI1A and ST3GAL3

Data Source:
BioGRID (two hybrid)

		VTI1A	ST3GAL3
Description		vesicle transport through interaction with t-SNAREs 1A	ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Late Endosome Membrane Trans-Golgi Network Membrane Neuronal Cell Body Intracellular Membrane-bounded Organelle Neuron Projection Terminus Perinuclear Region Of Cytoplasm	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity
	Biological Process	Protein Targeting To Vacuole Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Autophagy Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Voluntary Musculoskeletal Movement Golgi Ribbon Formation	Protein Glycosylation O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness ( 30510157) Cognitive decline (age-related) ( 28078323) Colorectal cancer ( 26965516 30529582 25105248) Colorectal cancer or advanced adenoma ( 30510241) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Evening vs. morning chronotype (sMEQ score) ( 32579418) Heel bone mineral density ( 30598549) Lung cancer ( 23143601) Multiple sclerosis ( 23412934) Non-glioblastoma glioma ( 28346443 26424050) Non-small cell lung cancer ( 31326317) QRS duration ( 30679814 27577874 31251759 27659466) Refractive error ( 32231278)	Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256)
Interacting Genes		2 interacting genes: STX16 TMBIM6	5 interacting genes: ACTG1 RPL8 SCAMP2 TTR ZBTB5
Entrez ID		143187	6487
HPRD ID		18290	05930
Ensembl ID		ENSG00000151532	ENSG00000126091
Uniprot IDs		Q96AJ9	A0A2R8Y732 Q11203
PDB IDs
Enriched GO Terms of Interacting Partners?
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