C2orf73 and ERLEC1

Data Source:
HPRD (in vitro, two hybrid)

		C2orf73	ERLEC1
Description		chromosome 2 open reading frame 73	endoplasmic reticulum lectin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function		Protein Binding Unfolded Protein Binding
	Biological Process		ERAD Pathway Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 30072576 29875488) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		3 interacting genes: FCHSD2 HSPB1 SH3BP4	1 interacting genes: STK11
Entrez ID		129852	27248
HPRD ID		13446	10310
Ensembl ID		ENSG00000177994	ENSG00000068912
Uniprot IDs		Q8N5S3	Q96DZ1 V9HWD3
PDB IDs
Enriched GO Terms of Interacting Partners?
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