WFDC12 and SULF2

Data Source:
BioGRID (affinity chromatography technology)

		WFDC12	SULF2
Description		WAP four-disulfide core domain 12	sulfatase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space Endoplasmic Reticulum Golgi Stack Plasma Membrane Cell Surface
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Arylsulfatase Activity Calcium Ion Binding Glycosaminoglycan Binding N-acetylglucosamine-6-sulfatase Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response	Kidney Development Chondrocyte Development Glomerular Filtration Response To Wounding Positive Regulation Of Vascular Endothelial Growth Factor Production Esophagus Smooth Muscle Contraction Positive Regulation Of Wnt Signaling Pathway Heparan Sulfate Proteoglycan Metabolic Process Glomerular Basement Membrane Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Embryonic Skeletal System Development Cartilage Development Bone Development Innervation Positive Regulation Of Canonical Wnt Signaling Pathway Liver Regeneration Regulation Of Hepatocyte Proliferation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Apolipoprotein A1 levels ( 32203549) Attention deficit hyperactivity disorder (time to onset) ( 18937294) Cerebrospinal fluid AB1-42 levels ( 28247064) Depressive symptoms x herpes simplex 1 infection interaction ( 32564518) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) L-selectin levels ( 25576479) Nephrotic syndrome (acquired) ( 21441931) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		6 interacting genes: ASPH SGTA SGTB SLC39A7 UBQLN1 UBQLN2
Entrez ID		128488	55959
HPRD ID		15674	18130
Ensembl ID		ENSG00000168703	ENSG00000196562
Uniprot IDs		Q8WWY7	Q8IWU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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