ATP6V1G3 and LMAN2L

Data Source:
BioGRID (affinity chromatography technology)

		ATP6V1G3	LMAN2L
Description		ATPase H+ transporting V1 subunit G3	lectin, mannose binding 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Protein Binding Mannose Binding Metal Ion Binding
	Biological Process	Insulin Receptor Signaling Pathway Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs		Tiludronic acid
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide) ( 23648065) Asthma ( 31959851) Body mass index ( 28552196) General risk tolerance (MTAG) ( 30643258) Mean corpuscular hemoglobin ( 29403010 20139978) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)
Interacting Genes		1 interacting genes: OTX2	2 interacting genes: MAL ZDHHC17
Entrez ID		127124	81562
HPRD ID		16526	17286
Ensembl ID		ENSG00000151418	ENSG00000114988
Uniprot IDs		Q96LB4	B4DI83 B4DVH1 B4E308 Q9H0V9
PDB IDs
Enriched GO Terms of Interacting Partners?
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