CNN1 and ECSIT

Data Source:
BioGRID (genetic interference)

		CNN1	ECSIT
Description		calponin 1	ECSIT signaling integrator
Image			No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Focal Adhesion	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding	Protein Binding
	Biological Process	Regulation Of Smooth Muscle Contraction Actomyosin Structure Organization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation	Mitochondrial Respiratory Chain Complex I Assembly Innate Immune Response Regulation Of Oxidoreductase Activity Regulation Of Protein Complex Stability
Pathways			MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 27098658)	Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		15 interacting genes: ACTA1 ADRB2 CALM1 CCHCR1 COG6 DNMBP FYN MYO1A NCAPD2 PLRG1 PRKCE SYCE1 TFPT TPM3 TUBB	52 interacting genes: A2M AP1M2 APOE APP BFSP2 BLMH C1orf109 CDC37 CEP55 CTNNA3 CYP2C18 CYP2C8 CYP2C9 DNAJB1 DTX2 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH GEM IFIT3 IFIT5 IMMT LONP1 LOXL4 MAGEB2 MAST1 MKRN3 NFKB1 NXF1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TARS3 TRAF6 TRIM59 TSSK3
Entrez ID		1264	51295
HPRD ID		02884	12225
Ensembl ID		ENSG00000130176	ENSG00000130159
Uniprot IDs		B7Z7E1 P51911 Q53FP8 V9HWA5	Q9BQ95
PDB IDs		1WYP
Enriched GO Terms of Interacting Partners?
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