CNGA1 and BBS7

Data Source:
BioGRID (affinity chromatography technology)

		CNGA1	BBS7
Description		cyclic nucleotide gated channel subunit alpha 1	Bardet-Biedl syndrome 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane	Photoreceptor Outer Segment Nucleus Centrosome Cytosol Axoneme Membrane BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane
	Molecular Function	Intracellular CAMP-activated Cation Channel Activity Intracellular CGMP-activated Cation Channel Activity Protein Binding CGMP Binding	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding
	Biological Process	Visual Perception Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Cation Transmembrane Transport	Eye Development Heart Looping Regulation Of Transcription By RNA Polymerase II Smoothened Signaling Pathway Determination Of Left/right Symmetry Brain Development Visual Perception Protein Localization Protein Transport Melanosome Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fat Cell Differentiation Intracellular Transport Digestive Tract Morphogenesis Pigment Granule Aggregation In Cell Center Limb Development Cilium Assembly Primary Palate Development Non-motile Cilium Assembly
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	BBSome-mediated cargo-targeting to cilium
Drugs		Dequalinium
Diseases		Retinitis pigmentosa (RP)	Bardet-Biedl syndrome (BBS)
GWAS			Asthma ( 31959851)
Interacting Genes		1 interacting genes: SLC24A1	4 interacting genes: FHOD1 JUN KRT18 PAX2
Entrez ID		1259	55212
HPRD ID		00445	07399
Ensembl ID		ENSG00000198515	ENSG00000138686
Uniprot IDs		A0A024R9X3 P29973	Q8IWZ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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