ZPBP2 and PGAP3

Data Source:
BioGRID (proximity labelling technology)

		ZPBP2	PGAP3
Description		zona pellucida binding protein 2	post-GPI attachment to proteins phospholipase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Zona Pellucida Receptor Complex Extracellular Region Nucleus Cell Body	Golgi Membrane Integral Component Of Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane
	Molecular Function		Protein Binding Hydrolase Activity, Acting On Ester Bonds
	Biological Process	Acrosome Assembly Negative Regulation Of Immunoglobulin Production Sphingolipid Metabolic Process Binding Of Sperm To Zona Pellucida Circadian Regulation Of Gene Expression Membrane Lipid Catabolic Process	GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Adult asthma ( 30787307) Allergic rhinitis ( 30013184) Asthma ( 31959851 27182965 31619474 28461288) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 29273806) Asthma (time to onset) ( 27130862) Asthma or allergic disease (pleiotropy) ( 29785011) Atrial fibrillation ( 30061737 29892015) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908 21102463) Fractional exhaled nitric oxide (childhood) ( 24315451) Inflammatory bowel disease ( 28067908 23128233) Neurociticism ( 29500382) Primary biliary cholangitis ( 23000144 20639880 30643196) Primary biliary cirrhosis ( 22961000) Refractive error ( 32231278) Rheumatoid arthritis ( 30572963) Subcutaneous adipose tissue ( 27918534) Systemic sclerosis ( 30572963) Ulcerative colitis ( 28067908 20228799 21297633)	Asthma ( 31959851 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Triglyceride levels ( 30108155)
Interacting Genes
Entrez ID		124626	93210
HPRD ID		18365	15118
Ensembl ID		ENSG00000186075	ENSG00000161395
Uniprot IDs		Q6X784	A8K0P7 J3QKU0 Q96FM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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