TMEM219 and ZNF785

Data Source:
BioGRID (proximity labelling technology)

		TMEM219	ZNF785
Description		transmembrane protein 219	zinc finger protein 785
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands	Generic Transcription Pathway
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 28991256 25056061 29483656)	Eosinophil counts ( 27863252)
Interacting Genes			22 interacting genes: CABP2 CBY2 CCDC136 CCNDBP1 CEP70 EHMT2 GOLGA6L9 HOOK1 KIFC3 KRT36 KRTAP10-1 KRTAP10-5 KRTAP12-2 MDFI MID2 MTUS2 PNMA2 PRR7 STX1A STX2 TPM2 TRIP6
Entrez ID		124446	146540
HPRD ID		18546	08120
Ensembl ID		ENSG00000149932	ENSG00000197162
Uniprot IDs		A0A024R618 Q86XT9	A0A024QZC7 A8K8V0
PDB IDs
Enriched GO Terms of Interacting Partners?
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