TMEM219 and PRRT2

Data Source:
BioGRID (affinity chromatography technology)

		TMEM219	PRRT2
Description		transmembrane protein 219	proline rich transmembrane protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Vesicle Presynaptic Membrane Dendritic Spine Axon Terminus Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding Syntaxin-1 Binding
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Negative Regulation Of Short-term Synaptic Potentiation
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes			8 interacting genes: AQP6 F2RL1 GPRC5D MFSD14B SLC10A6 SMIM5 SNAP25 TLCD4
Entrez ID		124446	112476
HPRD ID		18546	13995
Ensembl ID		ENSG00000149932	ENSG00000167371
Uniprot IDs		A0A024R618 Q86XT9	Q7Z6L0
PDB IDs
Enriched GO Terms of Interacting Partners?
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