HYKK and DNAJA4

Data Source:
HPRD (in vivo)

		HYKK	DNAJA4
Description		hydroxylysine kinase	DnaJ heat shock protein family (Hsp40) member A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Cytosol Membrane
	Molecular Function	Amino Acid Kinase Activity Hydroxylysine Kinase Activity	Protein Binding ATP Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Lysine Catabolic Process Phosphorylation	Response To Heat Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Protein Refolding Negative Regulation Of Inclusion Body Assembly
Pathways		Lysine catabolism	HSP90 chaperone cycle for steroid hormone receptors (SHR)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 29483656)	Eyebrow thickness ( 26926045) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		3 interacting genes: GMCL1 LAGE3 TRIP6	3 interacting genes: BANP ERG SH3BP4
Entrez ID		123688	55466
HPRD ID		12515	09920
Ensembl ID		ENSG00000188266	ENSG00000140403
Uniprot IDs		A2RU49	Q69YX3 Q8WW22
PDB IDs
Enriched GO Terms of Interacting Partners?
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