ADD3 and PENK

Data Source:
BioGRID (two hybrid)

		ADD3	PENK
Description		adducin 3	proenkephalin
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Cytosol Cytoskeleton Plasma Membrane Brush Border Cell-cell Junction Cell Cortex Postsynaptic Density Membrane	Extracellular Region Endoplasmic Reticulum Lumen Plasma Membrane Dendrite Symmetric Synapse Chromaffin Granule Lumen Synaptic Vesicle Lumen Neuronal Cell Body Perikaryon Axon Terminus Cell Body Fiber Neuronal Dense Core Vesicle Lumen
	Molecular Function	Structural Constituent Of Cytoskeleton Calmodulin Binding Actin Filament Binding	Opioid Peptide Activity Neuropeptide Hormone Activity Opioid Receptor Binding
	Biological Process	Barbed-end Actin Filament Capping Transmembrane Transport	Osteoblast Differentiation Behavioral Fear Response Response To Hypoxia Startle Response Aggressive Behavior Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Sensory Perception Response To Radiation Response To Toxic Substance Glial Cell Proliferation Sensory Perception Of Pain Response To Estradiol Response To Lipopolysaccharide Cellular Response To Oxidative Stress Response To Nicotine Locomotory Exploration Behavior Response To Morphine Post-translational Protein Modification Cellular Protein Metabolic Process Response To Ethanol Response To Calcium Ion General Adaptation Syndrome, Behavioral Process Cellular Response To Vitamin D Cellular Response To CAMP Cellular Response To Transforming Growth Factor Beta Stimulus Response To Epinephrine Cellular Response To Virus Synaptic Signaling Via Neuropeptide Positive Regulation Of Behavioral Fear Response
Pathways		Miscellaneous transport and binding events	Peptide ligand-binding receptors Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (i) signalling events Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Biliary atresia ( 20460270) Bipolar disorder ( 31043756 28072414) Cutaneous melanoma or hair colour ( 32341527) Metabolite levels ( 23823483) Neutrophil count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010)	Blood protein levels ( 30072576 29875488) Height ( 18391951) Problematic alcohol use ( 32451486) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Suicide in bipolar disorder ( 25917933)
Interacting Genes		6 interacting genes: AGTR1 ATXN1 HSPB1 OPRM1 PRKCA UBE2I
Entrez ID		120	5179
HPRD ID		03339	08837
Ensembl ID		ENSG00000148700	ENSG00000181195
Uniprot IDs		Q53FL4 Q59EK1 Q5VU08 Q9UEY8	A0A024R7V4 P01210
PDB IDs			1PLW 1PLX 2LWC 5E33 5E3A
Enriched GO Terms of Interacting Partners?
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