CLCN3 and ANXA10

Data Source:
BioGRID (genetic interference)

		CLCN3	ANXA10
Description		chloride voltage-gated channel 3	annexin A10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle External Side Of Plasma Membrane Cell Surface Endosome Membrane Vesicle Membrane Membrane Integral Component Of Membrane Secretory Granule Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Ruffle Membrane Specific Granule Intracellular Membrane-bounded Organelle Axon Terminus Phagocytic Vesicle Recycling Endosome Glutamatergic Synapse	Cytoplasm
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Antiporter Activity Solute:proton Antiporter Activity PDZ Domain Binding Volume-sensitive Chloride Channel Activity	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Regulation Of PH Phagocytosis, Engulfment Adult Locomotory Behavior Synaptic Transmission, Glutamatergic Photoreceptor Cell Maintenance Negative Regulation Of Cell Volume Endosomal Lumen Acidification Synaptic Transmission, GABAergic Synaptic Vesicle Lumen Acidification Chloride Transmembrane Transport Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Schizophrenia ( 28991256 25056061 29483656 30285260)	Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pursuit maintenance gain ( 29064472) Verbal declarative memory ( 25648963)
Interacting Genes		6 interacting genes: CFTR DNAJC5 GOPC HSPB1 PDZK1 SLC9A3R1	2 interacting genes: BLVRB EDC3
Entrez ID		1182	11199
HPRD ID		02785	09724
Ensembl ID		ENSG00000109572	ENSG00000109511
Uniprot IDs		B3KXK0 P51790	Q9UJ72
PDB IDs
Enriched GO Terms of Interacting Partners?
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