CLCN2 and BRD2

Data Source:
BioGRID (affinity chromatography technology)

		CLCN2	BRD2
Description		chloride voltage-gated channel 2	bromodomain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Voltage-gated Chloride Channel Activity	Chromatin Binding Protein Serine/threonine Kinase Activity Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Chloride Transport Regulation Of Aldosterone Biosynthetic Process Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Retina Development In Camera-type Eye Cell Differentiation Involved In Salivary Gland Development Chloride Transmembrane Transport	Neural Tube Closure Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Spermatogenesis Viral Process
Pathways		Stimuli-sensing channels	RUNX3 regulates p14-ARF
Drugs		Lubiprostone Cobiprostone
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		General cognitive ability ( 29844566)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)
Interacting Genes		4 interacting genes: ATXN1 FHL3 PPP1CA UBQLN1	8 interacting genes: E2F1 E2F2 H2BC21 H2BU1 H4-16 SPOP TBP TOP1
Entrez ID		1181	6046
HPRD ID		02782	03326
Ensembl ID		ENSG00000114859	ENSG00000204256
Uniprot IDs		P51788	A0A024RCR5 A0A1U9X7A8 P25440 X5CF57
PDB IDs			1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6JKE 6K04 6K05 6MO7 6MO8 6MO9 6MOA 6ONY 6SWO 6SWP 6TQ1 6TQ2 6U61 6U71 6U8H 6ULQ 6VIY 6YTM 6Z7F 6Z8P 6ZB0 6ZB1 6ZB2
Enriched GO Terms of Interacting Partners?
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