RBP7 and NPHP4

Data Source:
BioGRID (biochemical)

		RBP7	NPHP4
Description		retinol binding protein 7	nephrocystin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding Retinal Binding Retinol Binding	Structural Molecule Activity Protein Binding
	Biological Process		Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone
Pathways			Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS			Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)
Interacting Genes		5 interacting genes: APPL2 DAPP1 DOK4 HSH2D NCKIPSD	2 interacting genes: NPHP1 RPGRIP1
Entrez ID		116362	261734
HPRD ID		16355	06238
Ensembl ID		ENSG00000162444	ENSG00000131697
Uniprot IDs		Q96R05	B3KW36 O75161
PDB IDs		1LPJ 6AT8 6E6K
Enriched GO Terms of Interacting Partners?
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