FCRL3 and FCRL1

Data Source:
BioGRID (affinity chromatography technology)

		FCRL3	FCRL1
Description		Fc receptor like 3	Fc receptor like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface	Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding	Transmembrane Signaling Receptor Activity Coreceptor Activity
	Biological Process	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity	Cell Surface Receptor Signaling Pathway B Cell Activation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)	Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 24076602)
Interacting Genes		11 interacting genes: AGPAT4 CMTM5 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70
Entrez ID		115352	115350
HPRD ID		07352	07350
Ensembl ID		ENSG00000160856	ENSG00000163534
Uniprot IDs		Q96P31	Q96LA6
PDB IDs
Enriched GO Terms of Interacting Partners?
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