CKB and GPR65

Data Source:
BioGRID (genetic interference)

		CKB	GPR65
Description		creatine kinase B	G protein-coupled receptor 65
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Dendrite Neuronal Cell Body Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding	G Protein-coupled Receptor Activity
	Biological Process	Creatine Metabolic Process Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process	Apoptotic Process Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Response To Acidic PH Actin Cytoskeleton Reorganization Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Stress Fiber Assembly Activation Of GTPase Activity
Pathways		Creatine metabolism	Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Ankylosing spondylitis ( 23749187) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease ( 28067908 21102463) Degraded stimulus continuous performance test score ( 31596458) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Eosinophil percentage of white cells ( 32888494) Food antigen IgG levels ( 24962563) Inflammatory bowel disease ( 28067908 23128233) Multiple sclerosis ( 21833088) Parkinson's disease ( 32201043) Takayasu arteritis ( 25604533)
Interacting Genes		15 interacting genes: ACD ARIH2 ASB9 CKM ERBB2 GOLGA2 ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63
Entrez ID		1152	8477
HPRD ID		00423	07057
Ensembl ID		ENSG00000166165	ENSG00000140030
Uniprot IDs		G3V4N7 P12277 V9HWH2	B5B0C2 Q8IYL9
PDB IDs		3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
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