SCRG1 and NPHP4

Data Source:
BioGRID (affinity chromatography technology)

		SCRG1	NPHP4
Description		stimulator of chondrogenesis 1	nephrocystin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus Neuron Projection Terminus	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Nervous System Development	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone
Pathways			Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Chin dimples ( 27182965) Diverticular disease ( 30177863) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Refractive error ( 32231278)	Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)
Interacting Genes		4 interacting genes: CATSPER1 FAM209A MANBAL TMEM14B	2 interacting genes: NPHP1 RPGRIP1
Entrez ID		11341	261734
HPRD ID		11932	06238
Ensembl ID		ENSG00000164106	ENSG00000131697
Uniprot IDs		O75711 Q6FGG5	B3KW36 O75161
PDB IDs
Enriched GO Terms of Interacting Partners?
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