PRRT2 and TMEM219

Data Source:
BioGRID (affinity chromatography technology)

		PRRT2	TMEM219
Description		proline rich transmembrane protein 2	transmembrane protein 219
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Vesicle Presynaptic Membrane Dendritic Spine Axon Terminus Presynapse Postsynaptic Density Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Syntaxin-1 Binding	Protein Binding
	Biological Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Negative Regulation Of Short-term Synaptic Potentiation	Apoptotic Process Regulation Of Apoptotic Process
Pathways			TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		8 interacting genes: AQP6 F2RL1 GPRC5D MFSD14B SLC10A6 SMIM5 SNAP25 TLCD4
Entrez ID		112476	124446
HPRD ID		13995	18546
Ensembl ID		ENSG00000167371	ENSG00000149932
Uniprot IDs		Q7Z6L0	A0A024R618 Q86XT9
PDB IDs
Enriched GO Terms of Interacting Partners?
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