CEP250 and TTI1

Data Source:
BioGRID (biochemical)

		CEP250	TTI1
Description		centrosomal protein 250	TELO2 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Centrosome Centriole Microtubule Organizing Center Cytosol Protein-containing Complex Ciliary Basal Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm TORC1 Complex TORC2 Complex ASTRA Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Protein Kinase Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Centriole-centriole Cohesion Regulation Of Centriole-centriole Cohesion Protein Localization To Organelle Detection Of Light Stimulus Involved In Visual Perception Cilium Assembly Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Protein Localization To Centrosome Non-motile Cilium Assembly	Regulation Of TOR Signaling
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Brain morphology (MOSTest) ( 32665545) Height ( 25429064 18391951) Refractive error ( 32231278) Ulcerative colitis ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APP ATF7IP KAT2B NEK2 PLEKHA5 YWHAG	2 interacting genes: RXFP4 SUMO2
Entrez ID		11190	9675
HPRD ID		09877	13799
Ensembl ID		ENSG00000126001	ENSG00000101407
Uniprot IDs		Q9BV73	O43156
PDB IDs		6OQA
Enriched GO Terms of Interacting Partners?
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