LMAN2 and TSPAN17

Data Source:
BioGRID (affinity chromatography technology)

		LMAN2	TSPAN17
Description		lectin, mannose binding 2	tetraspanin 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Plasma Membrane Cell Surface COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Ubiquitin Ligase Complex Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Mannose Binding Carbohydrate Binding Heat Shock Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Enzyme Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endoplasmic Reticulum Organization Golgi Organization Protein Transport Positive Regulation Of Phagocytosis	Protein Ubiquitination Protein Maturation Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Allergic disease (asthma, hay fever or eczema) ( 29083406) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Blood protein levels ( 30072576) Chronic kidney disease ( 20383146) High light scatter reticulocyte count ( 32888494) Metabolite levels (small molecules and protein measures) ( 27005778) Red blood cell count ( 27863252) Reticulocyte count ( 32888494) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Urinary calcium excretion ( 31993563) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ATP13A2 FRAT1 MAPK9 SUPT5H
Entrez ID		10960	26262
HPRD ID		17285	18198
Ensembl ID		ENSG00000169223	ENSG00000048140
Uniprot IDs		A0A384NPY7 Q12907	A0A024R7Q6 J3KNG2 Q96FV3
PDB IDs
Enriched GO Terms of Interacting Partners?
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