STARD3 and SLC39A7

Data Source:
BioGRID (affinity chromatography technology)

		STARD3	SLC39A7
Description		StAR related lipid transfer domain containing 3	solute carrier family 39 member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Lipid Metabolic Process C21-steroid Hormone Biosynthetic Process Mitochondrial Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum Intermembrane Lipid Transfer	Cellular Zinc Ion Homeostasis Zinc Ion Transmembrane Transport
Pathways		Pregnenolone biosynthesis	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)
Interacting Genes		6 interacting genes: AQP6 CREB3 DAPK1 GOPC LMNA RNF170	29 interacting genes: AQP6 BIK CLCA4 CRCT1 ERCC6 GJA8 KCNF1 KRTAP1-3 KRTAP5-7 KRTAP9-2 LCE1A LCE1C LCE1F LCE2C LCE2D LCE4A LCE5A LELP1 RGS17 RSPO2 SHISAL1 SLC34A2 SMCP SPRY3 TMEM14B TNFRSF10D UNC93A WFDC12 YY1
Entrez ID		10948	7922
HPRD ID		06132	09028
Ensembl ID		ENSG00000131748	ENSG00000112473
Uniprot IDs		Q14849	A0A024RCX7 B4DZZ8 Q92504
PDB IDs		1EM2 2I92 5I9J
Enriched GO Terms of Interacting Partners?
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