TUBGCP2 and INPP5A

Data Source:
BioGRID (biochemical)

		TUBGCP2	INPP5A
Description		tubulin gamma complex associated protein 2	inositol polyphosphate-5-phosphatase A
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Nucleoplasm Centrosome Microtubule Organizing Center Cytosol Cytoplasmic Microtubule Gamma-tubulin Small Complex Membrane	Plasma Membrane Membrane Dendrite
	Molecular Function	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Inositol-polyphosphate 5-phosphatase Activity Protein Binding PH Domain Binding Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Inositol Phosphate Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Inositol Phosphate-mediated Signaling Negative Regulation Of Neuron Death
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS		Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)	Gait speed in old age ( 28077804) Heel bone mineral density ( 30598549 28869591) Migraine ( 27182965) Primary sclerosing cholangitis ( 27992413) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 30275531)
Interacting Genes		3 interacting genes: KIF14 PCNT UBC	3 interacting genes: PLEK TEAD2 YWHAZ
Entrez ID		10844	3632
HPRD ID		18245	02521
Ensembl ID		ENSG00000130640	ENSG00000068383
Uniprot IDs		Q53EQ3 Q9BSJ2	Q14642
PDB IDs		6V6B 6V6S 6X0V
Enriched GO Terms of Interacting Partners?
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