SPINT3 and IFT52

Data Source:
BioGRID (enzymatic study)

		SPINT3	IFT52
Description		serine peptidase inhibitor, Kunitz type 3	intraflagellar transport 52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip Ciliary Base
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Receptor Antagonist Activity Transforming Growth Factor Beta Binding	Protein C-terminus Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Receptor Activity	Neural Tube Formation Heart Looping Smoothened Signaling Pathway Dorsal/ventral Pattern Formation Intraciliary Anterograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Cilium Assembly Regulation Of Protein Processing Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Brain structure ( 20171287)	Mean reticulocyte volume ( 32888494)
Interacting Genes
Entrez ID		10816	51098
HPRD ID		19468	12789
Ensembl ID		ENSG00000101446	ENSG00000101052
Uniprot IDs		P49223	Q9Y366
PDB IDs
Enriched GO Terms of Interacting Partners?
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