ATP5MG and SRD5A2

Data Source:
BioGRID (affinity chromatography technology)

		ATP5MG	SRD5A2
Description		ATP synthase membrane subunit g	steroid 5 alpha-reductase 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	3-oxo-5-alpha-steroid 4-dehydrogenase Activity Protein Binding Sterol 5-alpha Reductase Activity Oxidoreductase Activity Testosterone Dehydrogenase [NAD(P)] Activity Cholestenone 5-alpha-reductase Activity
	Biological Process	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport	Steroid Biosynthetic Process Androgen Biosynthetic Process Cell-cell Signaling Androgen Metabolic Process Male Gonad Development Cell Differentiation Male Genitalia Development Testosterone Biosynthetic Process
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Androgen biosynthesis
Drugs		Artenimol Phenethyl Isothiocyanate	Spironolactone Azelaic acid Dutasteride Finasteride
Diseases			46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS			Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Idiopathic pulmonary fibrosis ( 29066090) Inflammatory biomarkers ( 24182552) Male-pattern baldness ( 29146897 27182965 28196072) Zinc levels ( 26025379)
Interacting Genes		2 interacting genes: MAGEC1 RHOU	2 interacting genes: CYSRT1 GNMT
Entrez ID		10632	6716
HPRD ID		09815	07390
Ensembl ID		ENSG00000167283	ENSG00000277893
Uniprot IDs		O75964	P31213
PDB IDs			7BW1
Enriched GO Terms of Interacting Partners?
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