NPC2 and EOLA1

Data Source:
HPRD (in vivo, in vitro)

		NPC2	EOLA1
Description		NPC intracellular cholesterol transporter 2	endothelium and lymphocyte associated ASCH domain 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protein Binding Cholesterol Binding Enzyme Binding Sterol Binding Cholesterol Transfer Activity	Protein Binding
	Biological Process	Cholesterol Metabolic Process Response To Virus Phospholipid Transport Sterol Transport Regulation Of Isoprenoid Metabolic Process Cholesterol Transport Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Neutrophil Degranulation Glycolipid Transport Intermembrane Lipid Transfer	Regulation Of Gene Expression Regulation Of Interleukin-6 Production
Pathways		Neutrophil degranulation LDL clearance
Drugs
Diseases		Niemann-Pick type C disease (NPC), including: Niemann-Pick disease, type C1; Niemann-Pick disease, type C2
GWAS		Advanced glycation end-product levels ( 26915486) Blood protein levels ( 29875488) Intraocular pressure ( 31959993) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: BARD1 BRCA1 DHDDS ECT2 ERRFI1 LIG4 PAXIP1 TRIM14 USP4	1 interacting genes: MT2A
Entrez ID		10577	91966
HPRD ID		03008	06625
Ensembl ID		ENSG00000119655	ENSG00000197620
Uniprot IDs		A0A024R6C0 P61916	Q8TE69
PDB IDs		5KWY 6W5V	5Y7D
Enriched GO Terms of Interacting Partners?
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