NPC2 and VASH1

Data Source:
BioGRID (affinity chromatography technology)

		NPC2	VASH1
Description		NPC intracellular cholesterol transporter 2	vasohibin 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Extracellular Space Cytoplasm Endoplasmic Reticulum Apical Part Of Cell
	Molecular Function	Protein Binding Cholesterol Binding Enzyme Binding Sterol Binding Cholesterol Transfer Activity	Actin Binding Metallocarboxypeptidase Activity Protein Binding
	Biological Process	Cholesterol Metabolic Process Response To Virus Phospholipid Transport Sterol Transport Regulation Of Isoprenoid Metabolic Process Cholesterol Transport Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Neutrophil Degranulation Glycolipid Transport Intermembrane Lipid Transfer	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Proteolysis Cell Cycle Arrest Response To Wounding Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Angiogenesis Labyrinthine Layer Blood Vessel Development Negative Regulation Of Lymphangiogenesis Regulation Of Cellular Senescence
Pathways		Neutrophil degranulation LDL clearance	Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases		Niemann-Pick type C disease (NPC), including: Niemann-Pick disease, type C1; Niemann-Pick disease, type C2
GWAS		Advanced glycation end-product levels ( 26915486) Blood protein levels ( 29875488) Intraocular pressure ( 31959993) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: BARD1 BRCA1 DHDDS ECT2 ERRFI1 LIG4 PAXIP1 TRIM14 USP4	1 interacting genes: DHPS
Entrez ID		10577	22846
HPRD ID		03008	12353
Ensembl ID		ENSG00000119655	ENSG00000071246
Uniprot IDs		A0A024R6C0 P61916	Q7L8A9
PDB IDs		5KWY 6W5V	6J4U 6J7B 6J8F 6J8N 6J8O 6J91 6J9H 6K81 6LPG 6NVQ 6OCF 6OCG 6OCH 6WSL
Enriched GO Terms of Interacting Partners?
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