PITRM1 and S100A7

Data Source:
BioGRID (affinity chromatography technology)

		PITRM1	S100A7
Description		pitrilysin metallopeptidase 1	S100 calcium binding protein A7
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Azurophil Granule Lumen Collagen-containing Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Enzyme Activator Activity Metallopeptidase Activity Zinc Ion Binding	Calcium Ion Binding Protein Binding Zinc Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Proteolysis Protein Targeting To Mitochondrion Protein Processing Regulation Of Catalytic Activity	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Antimicrobial Humoral Response Keratinocyte Differentiation Response To Lipopolysaccharide Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium Sequestering Of Metal Ion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis
Pathways		Mitochondrial protein import	Neutrophil degranulation Metal sequestration by antimicrobial proteins
Drugs			Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)	Blood protein levels ( 30072576)
Interacting Genes			8 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5
Entrez ID		10531	6278
HPRD ID		07142	02645
Ensembl ID		ENSG00000107959	ENSG00000143556
Uniprot IDs		Q5JRX3	P31151
PDB IDs		4L3T 4NGE 4RPU	1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ
Enriched GO Terms of Interacting Partners?
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