SLC25A17 and CACNA1S

Data Source:
BioGRID (affinity chromatography technology)

		SLC25A17	CACNA1S
Description		solute carrier family 25 member 17	calcium voltage-gated channel subunit alpha1 S
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Membrane	Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex T-tubule I Band L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Adenine Nucleotide Transmembrane Transporter Activity ATP Transmembrane Transporter Activity Protein Binding ADP Transmembrane Transporter Activity Coenzyme A Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FMN Transmembrane Transporter Activity Chaperone Binding NAD Transmembrane Transporter Activity AMP Transmembrane Transporter Activity	Voltage-gated Calcium Channel Activity Protein Binding Calmodulin Binding High Voltage-gated Calcium Channel Activity Metal Ion Binding
	Biological Process	Fatty Acid Alpha-oxidation Fatty Acid Beta-oxidation ADP Transport ATP Transport Fatty Acid Transport Coenzyme A Transmembrane Transport FAD Transmembrane Transport NAD Transmembrane Transport AMP Transport	Calcium Ion Transport Muscle Contraction Regulation Of Ion Transmembrane Transport Cardiac Conduction Calcium Ion Import Calcium Ion Transmembrane Transport Cellular Response To Caffeine
Pathways		Alpha-oxidation of phytanate Class I peroxisomal membrane protein import	NCAM1 interactions
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Isradipine Topiramate Nimodipine Nisoldipine Spironolactone Cinnarizine Magnesium sulfate Levomenthol Ethanol Felodipine Nitrendipine Miconazole Nifedipine Amiodarone Mibefradil Dronedarone Clevidipine Nilvadipine Trimebutine Pinaverium Aranidipine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases			Hypokalemic periodic paralysis (HypoPP)
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Coffee consumption ( 31046077) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Feeling nervous ( 29500382) Irritable mood ( 29500382) Low density lipoprotein cholesterol levels ( 29083408) Neurociticism ( 29500382) Refractive error ( 32231278)	Appendicular lean mass ( 33097823) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cardiac Troponin-T levels ( 31014085) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Permanent tooth development ( 21931568) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tooth agenesis ( 29364747) Ulcerative colitis ( 28067908 20228799) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		2 interacting genes: MEOX2 PEX19	8 interacting genes: CCDC106 CYSRT1 MEOX2 PDZD3 REL RIMS2 RYR1 SRI
Entrez ID		10478	779
HPRD ID		08425	00248
Ensembl ID		ENSG00000100372	ENSG00000081248
Uniprot IDs		B4DP73 B4DU97 F6RTR7 O43808	B1ALM3 Q13698
PDB IDs			2VAY 6B27
Enriched GO Terms of Interacting Partners?
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