SLC25A17 and CD55

Data Source:
BioGRID (two hybrid)

		SLC25A17	CD55
Description		solute carrier family 25 member 17	CD55 molecule (Cromer blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Membrane	Golgi Membrane Extracellular Region Plasma Membrane Cell Surface Transport Vesicle Secretory Granule Membrane Anchored Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Raft Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Adenine Nucleotide Transmembrane Transporter Activity ATP Transmembrane Transporter Activity Protein Binding ADP Transmembrane Transporter Activity Coenzyme A Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FMN Transmembrane Transporter Activity Chaperone Binding NAD Transmembrane Transporter Activity AMP Transmembrane Transporter Activity	Virus Receptor Activity Protein Binding Lipid Binding
	Biological Process	Fatty Acid Alpha-oxidation Fatty Acid Beta-oxidation ADP Transport ATP Transport Fatty Acid Transport Coenzyme A Transmembrane Transport FAD Transmembrane Transport NAD Transmembrane Transport AMP Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Complement Activation, Classical Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD4-positive, Alpha-beta T Cell Cytokine Production Neutrophil Degranulation Innate Immune Response Respiratory Burst Negative Regulation Of Complement Activation Viral Entry Into Host Cell Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways		Alpha-oxidation of phytanate Class I peroxisomal membrane protein import	Class B/2 (Secretin family receptors) Neutrophil degranulation COPI-mediated anterograde transport Regulation of Complement cascade
Drugs			Chloramphenicol
Diseases			Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Coffee consumption ( 31046077) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Feeling nervous ( 29500382) Irritable mood ( 29500382) Low density lipoprotein cholesterol levels ( 29083408) Neurociticism ( 29500382) Refractive error ( 32231278)	Blood protein levels ( 29875488 28240269) Refractive error ( 32231278) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		2 interacting genes: MEOX2 PEX19	6 interacting genes: ADGRE5 CD14 CR1 FYN GPLD1 LCK
Entrez ID		10478	1604
HPRD ID		08425	00500
Ensembl ID		ENSG00000100372	ENSG00000196352
Uniprot IDs		B4DP73 B4DU97 F6RTR7 O43808	B1AP13 P08174
PDB IDs			1H03 1H04 1H2P 1H2Q 1M11 1NWV 1OJV 1OJW 1OJY 1OK1 1OK2 1OK3 1OK9 1UOT 1UPN 2C8I 2QZD 2QZF 2QZH 3IYP 3J24 5FOA 6ILJ 6ILK 6LA5 7C9W
Enriched GO Terms of Interacting Partners?
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