MYL9 and SLC12A5

Data Source:
BioGRID (biochemical)

		MYL9	SLC12A5
Description		myosin light chain 9	solute carrier family 12 member 5
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Muscle Myosin Complex Z Disc	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Synapse Cell Periphery
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	Chloride Transmembrane Transporter Activity Potassium:chloride Symporter Activity
	Biological Process	Muscle Contraction Regulation Of Muscle Contraction Regulation Of Megakaryocyte Differentiation Platelet Aggregation	Ion Transport Cellular Ion Homeostasis Cell Volume Homeostasis Hypotonic Response Chemical Synaptic Transmission Learning Cellular Chloride Ion Homeostasis Multicellular Organism Growth Thermosensory Behavior Response To Drug Chloride Ion Homeostasis Potassium Ion Homeostasis Dendritic Spine Development Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Cation-coupled Chloride cotransporters
Drugs			Potassium chloride Bumetanide
Diseases
GWAS			Chronotype ( 30696823) Crohn's disease ( 28067908) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Systemic sclerosis ( 29293537) Triglyceride levels ( 32154731)
Interacting Genes		6 interacting genes: CDC42BPA HSPB1 LRRK2 MSGN1 MYH9 TXN2	2 interacting genes: CCR4 F2RL1
Entrez ID		10398	57468
HPRD ID		17619	09469
Ensembl ID		ENSG00000101335	ENSG00000124140
Uniprot IDs		A0A384NY64 P24844	Q9H2X9
PDB IDs			6M23
Enriched GO Terms of Interacting Partners?
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