B3GALT5 and ABCG1

Data Source:
BioGRID (enzymatic study)

		B3GALT5	ABCG1
Description		beta-1,3-galactosyltransferase 5	ATP binding cassette subfamily G member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Golgi Membrane Mitochondrion Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Recycling Endosome
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Acetylgalactosaminyltransferase Activity UDP-galactose:beta-N-acetylglucosamine Beta-1,3-galactosyltransferase Activity N-acetyllactosaminide Beta-1,3-N-acetylglucosaminyltransferase Activity	Protein Binding ATP Binding Phospholipid Binding Cholesterol Binding ATPase Activity Toxin Transmembrane Transporter Activity ABC-type Sterol Transporter Activity Protein Homodimerization Activity ADP Binding Protein Heterodimerization Activity Phosphatidylcholine Floppase Activity Cholesterol Transfer Activity Floppase Activity
	Biological Process	Protein Glycosylation Poly-N-acetyllactosamine Biosynthetic Process	Cholesterol Metabolic Process Response To Organic Substance Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Cholesterol Esterification Negative Regulation Of Cholesterol Storage Intracellular Cholesterol Transport Cholesterol Efflux Phospholipid Efflux Response To Lipid Lipid Translocation Low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Remodeling Glycoprotein Transport Cholesterol Homeostasis Amyloid Precursor Protein Catabolic Process Reverse Cholesterol Transport Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Protein Secretion Transmembrane Transport Phospholipid Homeostasis Intermembrane Lipid Transfer Toxin Transport Positive Regulation Of Amyloid-beta Formation
Pathways		Lewis blood group biosynthesis	ABC transporters in lipid homeostasis HDL remodeling NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs			ATP
Diseases
GWAS		Alcohol dependence ( 26365420) Corneal astigmatism ( 29422769) Metabolite levels ( 23823483) Obsessive-compulsive symptoms ( 26859814) Suicide risk ( 21041247)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Eating disorder in bipolar disorder ( 26433762) Gout ( 22179738) HDL cholesterol levels ( 32203549) Idiopathic osteonecrosis of the femoral head ( 28000841) Neuritic plaque ( 25188341)
Interacting Genes		3 interacting genes: CLEC2D DEFB103A DEFB103B	2 interacting genes: ABCG4 AQP6
Entrez ID		10317	9619
HPRD ID		06818	04355
Ensembl ID		ENSG00000183778	ENSG00000160179
Uniprot IDs		A0A0A0MS93 Q9Y2C3	P45844
PDB IDs
Enriched GO Terms of Interacting Partners?
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