NMUR1 and GIGYF2

Data Source:
BioGRID (biochemical)

		NMUR1	GIGYF2
Description		neuromedin U receptor 1	GRB10 interacting GYF protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite
	Molecular Function	Neuromedin U Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Receptor Activity Neuromedin U Binding	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding
	Biological Process	Calcium Ion Transport Chloride Transport Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Neuropeptide Signaling Pathway Calcium-mediated Signaling Inositol Phosphate-mediated Signaling	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases			Parkinson's disease (PD)
GWAS		Corneal astigmatism ( 30306274) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		2 interacting genes: NMS NMU	8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11
Entrez ID		10316	26058
HPRD ID		16039	11639
Ensembl ID		ENSG00000171596	ENSG00000204120
Uniprot IDs		Q9HB89	Q6Y7W6
PDB IDs			5NVL 5NVM
Enriched GO Terms of Interacting Partners?
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