VPS26C and IFNL1

Data Source:
BioGRID (biochemical)

		VPS26C	IFNL1
Description		VPS26 endosomal protein sorting factor C	interferon lambda 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome	Extracellular Region Extracellular Space Interleukin-28 Receptor Complex
	Molecular Function	Molecular_function Protein Binding	Signaling Receptor Binding Cytokine Activity Interleukin-28 Receptor Binding
	Biological Process	Intracellular Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Plasma Membrane	Negative Regulation Of Type 2 Immune Response Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Memory T Cell Differentiation Innate Immune Response Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Immune Response Defense Response To Virus
Pathways			Other interleukin signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CBLB DECR2 INCA1 LRIF1 MAML3 MAPK6 MDM4 MEI4 MEOX2 PTPN21 RAB39B TEPSIN XPA ZNF655	1 interacting genes: IFNLR1
Entrez ID		10311	282618
HPRD ID		10390	09588
Ensembl ID		ENSG00000157538	ENSG00000182393
Uniprot IDs		A8MTY9 A8MY26 O14972	Q8IU54
PDB IDs			3OG4 3OG6
Enriched GO Terms of Interacting Partners?
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