RCL1 and PUM3

Data Source:
BioGRID (biochemical)

		RCL1	PUM3
Description		RNA terminal phosphate cyclase like 1	pumilio RNA binding family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleoplasm Chromosome Nucleolus Endoplasmic Reticulum
	Molecular Function	Endoribonuclease Activity Protein Binding	DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Biological_process	Regulation Of Translation Regulation Of Protein ADP-ribosylation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 23263863 29403010 32888494 20139978 27863252 28017375 19862010) Mean corpuscular volume ( 23263863 29403010 32888494 20139978 27863252 28017375 19862010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Platelet count ( 26805783 22139419 24026423 23263863 29403010 31194788 32888494 20139978 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010 32888494 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252 28957414)	Depression ( 29700475) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		1 interacting genes: GOLGA2	4 interacting genes: APP CALM1 HPS6 ITGB1BP2
Entrez ID		10171	9933
HPRD ID		10189	08822
Ensembl ID		ENSG00000120158	ENSG00000080608
Uniprot IDs		Q5VZU3 Q9Y2P8	Q15397
PDB IDs			4WZR 4WZW
Enriched GO Terms of Interacting Partners?
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