ACTR1A and DPCD

Data Source:
BioGRID (proximity labelling technology)

		ACTR1A	DPCD
Description		actin related protein 1A	deleted in primary ciliary dyskinesia homolog (mouse)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Manchette Cytoplasm Centrosome Centriole Cytosol Dynactin Complex Microtubule Associated Complex Microtubule Cytoskeleton COPI-coated Vesicle Extracellular Exosome Cell Cortex Region	Extracellular Region Nucleus
	Molecular Function	Protein Binding ATP Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Spermatogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Ciliary Basal Body-plasma Membrane Docking	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation
Pathways		MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Mean corpuscular volume ( 32888494)
Interacting Genes		5 interacting genes: DCTN1 DCTN4 NUMA1 SPTBN1 SPTBN2	2 interacting genes: APP RUVBL2
Entrez ID		10121	25911
HPRD ID		05507	13247
Ensembl ID		ENSG00000138107	ENSG00000166171
Uniprot IDs		A0A384NQ21 P61163	Q5JQQ4 Q9BVM2
PDB IDs
Enriched GO Terms of Interacting Partners?
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