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USP28
Description
ubiquitin specific peptidase 28
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Nuclear Body
Protein-containing Complex
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Biological Process
DNA Damage Checkpoint
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Ras Protein Signal Transduction
Cell Population Proliferation
Response To Ionizing Radiation
Protein Deubiquitination
Protein Phosphopantetheinylation
Regulation Of Protein Stability
Cellular Response To UV
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways
Ub-specific processing proteases
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30643258
)
Low density lipoprotein cholesterol levels (
32154731
)
PR interval (
32439900
)
Interacting Genes
40 interacting genes:
ATXN3L
BAP1
CLSPN
ESPL1
HIF1A
JOSD1
KDM1A
MAP3K1
MDC1
MTNR1A
NSMCE2
OTUB1
OTUB2
PJA1
PLA2G2A
PRKD1
RFFL
SENP1
SENP8
STAM
STAMBP
SUMO2
TP53
TP53BP1
TRIM55
TRIM63
UBC
UCHL1
UCHL3
UCHL5
USP14
USP15
USP20
USP21
USP33
USP4
USP5
USP51
USP7
USP8
Entrez ID
57646
HPRD ID
15632
Ensembl ID
ENSG00000048028
Uniprot IDs
B4E3L3
Q96RU2
PDB IDs
2LVA
2MUU
6H4H
6H4I
6HEH
6HEI
6HEJ
6HEK
Enriched GO Terms of Interacting Partners
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