PLCL1

Description		phospholipase C like 1 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Phospholipase C Activity GABA Receptor Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Lipid Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Phosphatidylinositol-mediated Signaling Negative Regulation Of Cold-induced Thermogenesis Positive Regulation Of Receptor Binding
Pathways
Drugs		Quinacrine
Diseases
GWAS		Adult body size ( 32376654) Alcohol consumption ( 23743675) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 31361310 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain cytoarchitecture ( 20308991) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Central retinal arteriolar equivalent ( 31597446) Chin dimples ( 27182965) Chronotype ( 30696823) Coronary artery disease ( 26708285) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908 21102463) Dermatomyositis ( 23983088) Educational attainment ( 23722424) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip bone size ( 18776929) Intracranial aneurysm ( 18997786) Low high density lipoprotein cholesterol levels ( 26879886) Menarche (age at onset) ( 27182965 21102462) Mood instability ( 31168069) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Neutrophil count ( 21507922) Rheumatoid arthritis ( 32868391 30891314) Schizophrenia ( 25056061 29483656 30285260) Self-reported allergy ( 23817569) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 33536424 28714469) Total body bone mineral density ( 29304378) Ulcerative colitis ( 23128233) Urinary sodium excretion ( 31409800)
Novel Interacting Genes		1 novel interacting genes: CTLA4
Interacting Genes
Entrez ID		5334
HPRD ID		07041
Ensembl ID		ENSG00000115896
Uniprot IDs		Q15111
PDB IDs
Enriched GO Terms of Interacting Partners?
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