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PGF

Description placental growth factor
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Membrane
Molecular Function
  • Vascular Endothelial Growth Factor Receptor Binding
  • Protein Binding
  • Growth Factor Activity
  • Heparin Binding
  • Chemoattractant Activity
Biological Process
  • Response To Hypoxia
  • Positive Regulation Of Protein Phosphorylation
  • Positive Regulation Of Endothelial Cell Proliferation
  • Sprouting Angiogenesis
  • Signal Transduction
  • Cell-cell Signaling
  • Positive Regulation Of Cell Population Proliferation
  • Cell Differentiation
  • Vascular Endothelial Growth Factor Signaling Pathway
  • Positive Regulation Of Angiogenesis
  • Vascular Endothelial Growth Factor Receptor Signaling Pathway
  • Positive Chemotaxis
  • Induction Of Positive Chemotaxis
  • Positive Regulation Of Cell Division
  • Positive Regulation Of Mast Cell Chemotaxis
Pathways
  • VEGF ligand-receptor interactions
  • VEGF binds to VEGFR leading to receptor dimerization
Drugs
  • Aflibercept
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Mood instability ( 29187730)
  • Refractive error ( 32231278)
Interacting Genes 4 interacting genes: FLT1 NRP1 NRP2 VEGFA
Entrez ID 5228
HPRD ID 03076
Ensembl ID ENSG00000119630
Uniprot IDs G3XA84 P49763 Q53XY6 Q86TW6
PDB IDs 1FZV 1RV6
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025