MYLK

Description		myosin light chain kinase
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GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Lamellipodium Cleavage Furrow
	Molecular Function	Actin Binding Protein Kinase Activity Myosin Light Chain Kinase Activity Protein Binding Calmodulin Binding ATP Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Muscle Contraction Smooth Muscle Contraction Tonic Smooth Muscle Contraction Positive Regulation Of Cell Migration Bleb Assembly Positive Regulation Of Calcium Ion Transport Aorta Smooth Muscle Tissue Morphogenesis Cellular Hypotonic Response Positive Regulation Of Wound Healing
Pathways		Smooth Muscle Contraction RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs		Fostamatinib
Diseases		Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS		General cognitive ability ( 29844566)
Interacting Genes		15 interacting genes: ACTA1 ACTC1 APPBP2 CALM1 CAMK2G CTTN GOPC HSPB1 MAPK3 MLC1 PAK1 PAK2 PRKCA PRKG2 SRC
Entrez ID		4638
HPRD ID		02952
Ensembl ID		ENSG00000065534
Uniprot IDs		Q05B97 Q05B98 Q15746
PDB IDs		2CQV 2K0F 2YR3 5JQA 5JTH 6C6M
Enriched GO Terms of Interacting Partners?
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