MTR

Description		5-methyltetrahydrofolate-homocysteine methyltransferase
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Methionine Synthase Activity Cobalamin Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Nervous System Development Methionine Biosynthetic Process Cobalamin Metabolic Process Axon Regeneration Methylation Pteridine-containing Compound Metabolic Process Response To Axon Injury Cellular Response To Nitric Oxide
Pathways		Methylation Sulfur amino acid metabolism Cobalamin (Cbl, vitamin B12) transport and metabolism Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Drugs		Cyanocobalamin Tetrahydrofolic acid Methionine Hydroxocobalamin Mecobalamin Thimerosal
Diseases		Spina bifida
GWAS		Hallux valgus ( 32131869) Homocysteine levels ( 23824729)
Interacting Genes		2 interacting genes: CDKN2A DYNLL1
Entrez ID		4548
HPRD ID		01136
Ensembl ID		ENSG00000116984
Uniprot IDs		A0A6Q8PGK3 Q99707
PDB IDs		2O2K 4CCZ
Enriched GO Terms of Interacting Partners?
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