IL7

Description		interleukin 7
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Cytokine Activity Interleukin-7 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Cytokine-mediated Signaling Pathway T Cell Lineage Commitment Humoral Immune Response Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Animal Organ Morphogenesis Cytokine-mediated Signaling Pathway Positive Regulation Of B Cell Proliferation Positive Regulation Of Chemokine Production Interleukin-7-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Bone Resorption Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of Organ Growth Homeostasis Of Number Of Cells Within A Tissue Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Interleukin-7 signaling Interleukin-7 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 21833088) Neutrophil percentage of white cells ( 32888494 27863252) Suicide in bipolar disorder ( 25917933)
Novel Interacting Genes		1 novel interacting genes: LYN
Interacting Genes		5 interacting genes: APP CEBPE FBXO7 IL2RG IL7R
Entrez ID		3574
HPRD ID		00892
Ensembl ID		ENSG00000104432
Uniprot IDs		A0A0A0MTG5 A8K673 P13232 Q5FBX5
PDB IDs		1IL7 3DI2 3DI3
Enriched GO Terms of Interacting Partners?
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