IL34

Description		interleukin 34
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Inflammatory Response Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Chemotaxis Cytokine-mediated Signaling Pathway Positive Regulation Of MAP Kinase Activity Innate Immune Response Positive Regulation Of Macrophage Differentiation Positive Regulation Of Monocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Tyrosine Kinase Activity Interleukin-34-mediated Signaling Pathway Microglial Cell Proliferation Positive Regulation Of Macrophage Proliferation
Pathways		Other interleukin signaling
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Cerebrospinal P-tau181p levels ( 28247064) Diffuse cutaneous systemic sclerosis ( 29293537) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Intraocular pressure ( 29785010 30054594) Malaria ( 31844061)
Interacting Genes		3 interacting genes: ATXN1 LCE1F PTPRZ1
Entrez ID		146433
HPRD ID		14582
Ensembl ID		ENSG00000157368
Uniprot IDs		A0A024QZ87 Q6ZMJ4
PDB IDs		4DKC 4DKD 4DKE 4DKF
Enriched GO Terms of Interacting Partners?
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