CD46

Description		CD46 molecule
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GO Annotations	Cellular Component	Inner Acrosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Signaling Receptor Activity Cadherin Binding
	Biological Process	Adaptive Immune Response T Cell Mediated Immunity Complement Activation, Classical Pathway Single Fertilization Regulation Of Notch Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Complement Activation Interleukin-10 Production Positive Regulation Of Interleukin-10 Production Sequestering Of Extracellular Ligand From Receptor Positive Regulation Of T Cell Proliferation Positive Regulation Of Memory T Cell Differentiation Innate Immune Response Positive Regulation Of Regulatory T Cell Differentiation Viral Entry Into Host Cell Positive Regulation Of Transforming Growth Factor Beta Production
Pathways		Regulation of Complement cascade
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23326517) Biomedical quantitative traits ( 19396169) Chronic central serous retinopathy ( 30073298) Drug experimentation measurement ( 30718321) Early age-related macular degeneration ( 32843070) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Febrile seizures ( 25344690) Febrile seizures (MMR vaccine-related) ( 25344690) Heart rate ( 23583979) Immune response to measles vaccine (measles-specific neutralising antibody titre) ( 28289848) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Refractive error ( 32231278) Resting heart rate ( 29769521 27798624) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27841878 30578418) White blood cell count ( 32888494)
Novel Interacting Genes		2 novel interacting genes: NEK2 PRKACA
Interacting Genes		14 interacting genes: AGR3 ANKRD46 C3 DLG4 GPR37L1 ITGB1 LLGL1 MGAT5B MSN POU4F2 SRC TSPAN4 VTI1B YES1
Entrez ID		4179
HPRD ID		00406
Ensembl ID		ENSG00000117335
Uniprot IDs		P15529
PDB IDs		1CKL 1HR4 2O39 3INB 3L89 3O8E 5FO8
Enriched GO Terms of Interacting Partners?
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