FGF19

Description		fibroblast growth factor 19
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	MAPK Cascade Positive Regulation Of Protein Phosphorylation Nervous System Development Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Animal Organ Morphogenesis Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Differentiation Regulation Of Cell Migration Positive Regulation Of Glucose Import Positive Regulation Of JNK Cascade Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Bile Acid Biosynthetic Process
Pathways		PI3K Cascade PIP3 activates AKT signaling betaKlotho-mediated ligand binding FGFR4 ligand binding and activation Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade; FGFR4 FRS-mediated FGFR4 signaling SHC-mediated cascade:FGFR4 PI-3K cascade:FGFR4 Negative regulation of FGFR4 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs		Heparin
Diseases
GWAS		Breast cancer ( 20453838) Craniofacial microsomia ( 26853712) Height ( 31217584)
Interacting Genes		1 interacting genes: FGFR4
Entrez ID		9965
HPRD ID		04868
Ensembl ID		ENSG00000162344
Uniprot IDs		O95750
PDB IDs		1PWA 2P23 6KTR 6NFJ
Enriched GO Terms of Interacting Partners?
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