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FIG4

Description FIG4 phosphoinositide 5-phosphatase
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Lipid Droplet
  • Endosome Membrane
  • Early Endosome Membrane
  • Late Endosome Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Protein Binding
  • Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity
Biological Process
  • Phosphatidylinositol Biosynthetic Process
  • Phosphatidylinositol-3-phosphate Biosynthetic Process
  • Phosphatidylinositol Dephosphorylation
Pathways
  • Synthesis of PIPs at the Golgi membrane
  • Synthesis of PIPs at the Golgi membrane
  • Synthesis of PIPs at the early endosome membrane
  • Synthesis of PIPs at the early endosome membrane
  • Synthesis of PIPs at the late endosome membrane
  • Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Chronotype ( 30696823)
  • Depression in smokers ( 30219690)
  • Height ( 28552196)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Iron status biomarkers (transferrin saturation) ( 28334935)
  • Red cell distribution width ( 32888494)
Interacting Genes 3 interacting genes: APP GORASP2 VAC14
Entrez ID 9896
HPRD ID 11073
Ensembl ID ENSG00000112367
Uniprot IDs A0A6Q8PGB4 Q92562
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025